{"metadata":{"accession":"F8NNB0","id":"F8NNB0_SERL9","source_organism":{"taxId":"578457","scientificName":"Serpula lacrymans var. lacrymans (strain S7.9)","fullName":"Serpula lacrymans var. lacrymans (strain S7.9) (Dry rot fungus)"},"name":"Mediator of RNA polymerase II transcription subunit 17","description":["Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors"],"length":630,"sequence":"MEEQPWKNLKLSLERPYKDDKGEPIPVLLDIHPDGTHVYEPKEDPSKKLGQNLRRIFLERGLDFFDSGNRPNLQEESSTPLEKEDGAEGPEESQDISKPTMTPEELFQMRTEIMPQLYIALGEMSHAKELLSLLLASTNPSEPSPVPSLPPATLAATMVTKPAPIISVQAFDAQLNTGGKDEALRKAADLFKSAANSLESGRLRGEKYWLDALRIRRANWGLAPAPLPFGAPTGKGVDKTSKDFLISFGLEGSTAYFRRKAIGHMPTDPTTPDPLVFPHRQRTRLYISLNMVDAKGAQVESHNSIVASDDSSLEGSLAASQREIVEEEIFSTLIKEASSLPTASARVAERLIDIDAAQGMELRFELESLQSNNSQVATTMCDLIYSLLCALLLGMHTHKKLQRIGHAGVAHVLPQGSSSYTLLQPIIDLLQYQVFCERIRTELEKMVRALSKAEIPYNLRFDPIGESGEQLVRLFTGEDLDKKIGGEAILRIDNRHTLRLTLQSPSSLTAHLPQATLSIASIPQLVQLLSDEVEQCLLNKICEVGRQICEHVHGTWFVDMVSSRAVGRWEGCVLNFCVVYGKDYAIHSTAFRLRRVADQRPSLVETYTPDLSIPLVTWLHSIIAKTSLET","proteome":null,"gene":"MED17","go_terms":[{"identifier":"GO:0003712","name":"transcription coregulator activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006357","name":"regulation of transcription by RNA polymerase II","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016592","name":"mediator complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"6dd4dd1639e1b8c6a52ef96629b29bb1e4be94e3","counters":{"domain_architectures":3120,"entries":3,"isoforms":0,"proteomes":0,"sets":0,"structures":0,"taxa":1,"dbEntries":{"pfam":1,"panther":1,"interpro":1},"proteome":0,"taxonomy":1,"similar_proteins":3120}}}