{"metadata":{"accession":"F7I7E4","id":"F7I7E4_CALJA","source_organism":{"taxId":"9483","scientificName":"Callithrix jacchus","fullName":"Callithrix jacchus (White-tufted-ear marmoset)"},"name":"Regulator of chromosome condensation","description":["Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA"],"length":456,"sequence":"MPPKRIAKRKSPPEDAIPKNKKVKGARAAAFFAASCCVPGAHSCQGACGPGPPDQKTRPVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTEDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVTVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISREGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVRFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMTGKQLENRVVLSVSSGGQHTVLLVKDKEQS","proteome":"UP000008225","gene":"RCC1","go_terms":null,"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"dcfb3b90e34dacdf24d74323772bac8be4b5cb3b","counters":{"domain_architectures":15879,"entries":12,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"profile":1,"pfam":1,"panther":1,"prints":1,"prosite":2,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":15879}}}