{"metadata":{"accession":"F7E5Z4","id":"F7E5Z4_XENTR","source_organism":{"taxId":"8364","scientificName":"Xenopus tropicalis","fullName":"Xenopus tropicalis (Western clawed frog)"},"name":"Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha","description":["Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation"],"length":379,"sequence":"MLAPGAEEEGGEPEVQVMSQEQGEWECEQKVPSAPEMDGAGDSDLDYESLLASDRYILYRDRKEWADVKPVPQDDGPNPVVQIVYSEKFRDVYDYFRAVLQSDEKSERAFKLTTDAIELNAANYTVWHYRRVLLSSLQKDLREEMNYITAIIEEQPKNYQVWHHRRVLVELLKDPSEELEFTAEILSQDAKNYHAWQHRQWVIQEFNLWDNELQYVDLLLARDLRNNSAWNQRHFVISSTSGYSNSTILDREVQYALEMIKVAPHNESAWNYLRGILQERGMSEYPRLLDQIQCLQQTHSSPYLYAFLVDIYEDMLEKKCQNVEDTLNRALELCEILAKEKDTIRKEYWRYIGRSLTVKYGVNHTEKEEPINMDTVQPE","proteome":"UP000008143","gene":"fnta","go_terms":[{"identifier":"GO:0008318","name":"protein prenyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0018342","name":"protein prenylation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":2,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"26c858381acf809095f09e0223ab2e3de9465ba6","counters":{"domain_architectures":4415,"entries":6,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"profile":1,"pfam":1,"panther":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":4415}}}