{"metadata":{"accession":"F6V365","id":"F6V365_MONDO","source_organism":{"taxId":"13616","scientificName":"Monodelphis domestica","fullName":"Monodelphis domestica (Gray short-tailed opossum)"},"name":"E3 ubiquitin-protein ligase TRIM62","description":["E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C-type lectin receptors; leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways. E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2"],"length":441,"sequence":"MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILSARRAALPCQAHEKVKLFCLTDRALVCFFCDEPALHEQHQVTGIDDAFEELQRELKEQQKSLQDSEREHTEALQLLKRQLAETKVKSVRERERERERERETPLLHEMANSTFGQEGCRRLGFSGERATDPEHSPSRLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPVTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFGSGVHYWEVVVSEKTQWMIGLAHEAVSRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVKNKLEKVGVFLDYDKGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI","proteome":"UP000002280","gene":"TRIM62","go_terms":[{"identifier":"GO:0008270","name":"zinc ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"86f2cf1e635cac9e81855d99baf1f384f57ac39d","counters":{"domain_architectures":5410,"entries":34,"isoforms":0,"proteomes":1,"sets":6,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"cdd":3,"ssf":3,"smart":3,"pfam":4,"profile":3,"panther":1,"prints":1,"prosite":1,"interpro":12},"proteome":1,"taxonomy":1,"similar_proteins":5410}}}