{"metadata":{"accession":"F6SP59","id":"F6SP59_MACMU","source_organism":{"taxId":"9544","scientificName":"Macaca mulatta","fullName":"Macaca mulatta (Rhesus macaque)"},"name":"E3 ubiquitin-protein ligase","description":["E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation"],"length":360,"sequence":"MMAGCGEIDHSINMLPTNRKANESCSNTAPSLTVPECAICLQTCVHPVSLPCKHVFCYLCVKGASWLGKRCALCRQEIPEDFLDKPTLLSPEELKAASRGNGEYAWYYEGRNGWWQYDERTSRELEDAFSKGKKNTEMLIAGFLYVADLENMVQYRRNEHGRRRKIKRDIIDIPKKGVAGLRLDCDANTVNLARESSADGADSVSAQSGASVQPLVSSVRPLTSVDGQLTSPATPSPDASTSLEDSFAHLQLSGDSIAERSHRGEGEEDHESPSSGRVPAPDTSIEETESDASSDSENVSSAVVAQHSLTQQRLLVSNANQTVSDRSDQSGTDRSVAGGGTVSVSVRSRRPDGQCTVTEV","proteome":"UP000006718","gene":"RNF146","go_terms":[{"identifier":"GO:0008270","name":"zinc ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0061630","name":"ubiquitin protein ligase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0072572","name":"poly-ADP-D-ribose binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016055","name":"Wnt signaling pathway","category":{"code":"P","name":"biological_process"}}],"protein_evidence":2,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"0611f329f5c5c37ef6182b4a17ed2c1bf9ea41a5","counters":{"domain_architectures":1285,"entries":21,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"cdd":1,"pfam":2,"ssf":2,"smart":2,"profile":2,"panther":1,"prosite":1,"interpro":8},"proteome":1,"taxonomy":1,"similar_proteins":1285}}}