{"metadata":{"accession":"F6RA93","id":"F6RA93_HORSE","source_organism":{"taxId":"9796","scientificName":"Equus caballus","fullName":"Equus caballus (Horse)"},"name":"FUN14 domain-containing protein 2","description":["Binds directly and specifically 1,2-Diacyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-bisphosphate) (PIP3) leading to the recruitment of PIP3 to mitochondria and may play a role in the regulation of the platelet activation via AKT/GSK3B/cGMP signaling pathways. May act as transcription factor that regulates SREBP1 (isoform SREBP-1C) expression in order to modulate triglyceride (TG) homeostasis in hepatocytes"],"length":189,"sequence":"METSAPRAGSQLAATTARHSASYRAEPLRLSSRDELAEMAASAQGNFEGNFDSLDLAEFAKKQPWWRKLFGQESGPSAEKYSVATQLLIGGVTGWCTGFIFQKVGKLAATAVGGGFFLLQLANHTGYIKVDWQRVEKDMKKAKEQLKIRKSNQIPTEVKSKAEEVVSFVKKNVIVTGGFFGGFLLGMAS","proteome":"UP000002281","gene":"FUNDC2","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"69224364f88145b7fc68cd582d3205020ece1303","counters":{"domain_architectures":5301,"entries":3,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"panther":1,"pfam":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":5301}}}