{"metadata":{"accession":"F4BA37","id":"F4BA37_ACIHW","source_organism":{"taxId":"933801","scientificName":"Acidianus hospitalis (strain W1)","fullName":"Acidianus hospitalis (strain W1)"},"name":"ATP phosphoribosyltransferase","description":["Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity"],"length":299,"sequence":"MRFWLKLWVRFLKVAIPNKGRLQQPTLQFLTQVGIKPLASDERALMIPTSWDGVQLVMMRTEDIPNLVEAGAAEIGITGHDYVTESKADVEELIKLDFGKAKIVLAVPQNWDVENVEDLRRKKNGIRIATKYYNIAKEYLDKVDIDAKIVKISGAAEVMPSLGAADAIIDVVSTGTTLKLHGLKPIDEILQTYAVVIGNKYWMKSEEAERVNLVLTMMKGVISARGRKMIFMNVDDSKLEDVISSLPAMLSPAISRLSKTNAWEVITVAEESQLPEVIAKAKAAGARDIVVVNIEKVVK","proteome":"UP000008458","gene":"hisG","go_terms":[{"identifier":"GO:0000287","name":"magnesium ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003879","name":"ATP phosphoribosyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000105","name":"L-histidine biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"2e67110073aee079eb78374ed3effa0dc4234492","counters":{"domain_architectures":14110,"entries":19,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cathgene3d":2,"cdd":1,"pfam":2,"hamap":1,"ncbifam":2,"panther":1,"prosite":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":14110}}}