{"metadata":{"accession":"F3NF94","id":"F3NF94_9ACTN","source_organism":{"taxId":"996637","scientificName":"Streptomyces griseoaurantiacus M045","fullName":"Streptomyces griseoaurantiacus M045"},"name":"dITP/XTP pyrophosphatase","description":["Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions"],"length":200,"sequence":"MTRLILATRNAGKITELRAILAEAGLPHELVGADDFPEIPDVKETGVTFAENALLKAHALARATGLPAVADDSGLCVDVLGGAPGIFSARWAGRHGDDKANLDLLLAQLGDIDAPHRGAHFACAAALALPDGTERVVEGRLTGTLRHAPAGTNGFGYDPILQPEGDTRTCAELTPAEKNAISHRGQAFRALVPAVRELLG","proteome":"UP000003022","gene":"SGM_1808","go_terms":[{"identifier":"GO:0047429","name":"nucleoside triphosphate diphosphatase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009143","name":"nucleoside triphosphate catabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0017111","name":"ribonucleoside triphosphate phosphatase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"029a777975285995c6aff1e90978714c8929fb21","counters":{"domain_architectures":32111,"entries":10,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"pfam":1,"cdd":1,"hamap":1,"panther":1,"ncbifam":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":32111}}}