{"metadata":{"accession":"F2L7D4","id":"F2L7D4_BURGS","source_organism":{"taxId":"999541","scientificName":"Burkholderia gladioli (strain BSR3)","fullName":"Burkholderia gladioli (strain BSR3)"},"name":"Energy-dependent translational throttle protein EttA","description":["A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase"],"length":555,"sequence":"MAQYVFTMNRVGKIVPPKRQILKDISLSFFPGAKIGLLGLNGSGKSTLIRIMAGVDKDIEGEATPMPNLNIGYLPQEPQLDPSKTVREAVEEGLGDVFSAQKKLDEIYAAYAEPDADFDALAAEQAKYEAILAASDGGSPEQQIEIAADALRLPAWDAKIEHLSGGEKRRVALCKLLLEKPDMLLLDEPTNHLDAESVEWLEQFLTRFPGTVVAVTHDRYFLDNAAEWILELDRGHGIPWKGNYSSWLDQKEDRLKQEEATESARQKAIKKELEWVRQNPKGRQAKSKARIARFEELSSQEYQKRNETQEIFIPAGERLGNEVIEFKNVSKAYGDRLLIDDLSFKIPAGAIVGIIGPNGAGKSTLFRMLTGKEQPDSGEIVHGPTVKLAYVDQSRDALASDKTVFEEISGGADVLTVGKYETPSRAYIGRFNFKGGDQQKIVGNLSGGERGRLHLAKTLIAGGNVLLLDEPSNDLDVETLRALEDALLEFAGSVMVISHDRWFLDRIATHILAFEGDSQVVFFDGNYQEYEADKRARLGEEAAKPKRIRFKPISR","proteome":"UP000008316","gene":"ettA","go_terms":[{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016887","name":"ATP hydrolysis activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0045900","name":"negative regulation of translational elongation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"23709cf00441ec01b7e5c4492496e64144c74742","counters":{"domain_architectures":66202,"entries":18,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"profile":1,"ssf":1,"cdd":1,"pfam":2,"smart":1,"hamap":1,"ncbifam":2,"panther":1,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":66202}}}