{"metadata":{"accession":"C5P2S3","id":"C5P2S3_COCP7","source_organism":{"taxId":"222929","scientificName":"Coccidioides posadasii (strain C735)","fullName":"Coccidioides posadasii (strain C735) (Valley fever fungus)"},"name":"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3","description":["Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets"],"length":746,"sequence":"MAATAVNPLLKGTTSSNTRGLLRVIILAFIAAAAISSRLFSVIRFESIIHEFDPWFNFRATKYLVKHGFYSFWDWFDDRTWHPLGRVTGGTLYPGLMVTSGAIYHLLRFLSLPVDIRNICVLLAPAFSGLTALAMYLLTSEMSVSPSAGLLAAAFIGIAPGYISRSVAGSYDNEAIAIFLLIFTFFLWIKALKNGSIMWGALTALFYGYMVSAWGGYVFITNLIPLHAFVLICMGRYSSRLYISYTTWYALGTLASMQIPFVGFLPIRNSDHMAALGIFGLLQLVSFVEFLRSQVPGKQFQTVLTTLVLVIFGVAFLGLVLLTVTGVIAPWSGRFYSLWDTGYAKVHIPIIASVSEHQPTAWPAFFFDLSMLIWLFPAGVYMCFNKLKDEHVFVIIYAVLASYFAGVMVRLMLTLTPVVCVASALVVSHILETYLRLGSPDPDAQAKQANEKVSQSSPRSTRKRVVGVYSSVSKALVAGSFVVYLLLFVAHCTWVTSMAYSSPSVVLASKLPDGSQYIIDDYREAYYWLRQNTPKNAKIMSWWDYGYQIGGMADRPTLVDNNTWNNTHIATVGKALSSREEVSYPILRQHDVDYVLVVYGGLIGYSGDDINKFLWMVRIAEGLWPEEVKERDFFTDRGEYRVDDQATPTMRNSLMYKLCYYNVNALFPGGQGQDRVRGARLPSQGPQLTTLEEAFTSENWIIRIYKVKDLDNVGRDHNSAVAFEKGHKKKKAASLKRRGRRVLRTE","proteome":null,"gene":"CPC735_038750","go_terms":[{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0004576","name":"oligosaccharyl transferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009101","name":"glycoprotein biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"78e3a0cd558f3a53e19b0d8b754f34c3ad9e3f5c","counters":{"domain_architectures":5767,"entries":7,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"pfam":2,"cathgene3d":1,"panther":1,"interpro":3},"proteome":0,"taxonomy":1,"similar_proteins":5767}}}