{"metadata":{"accession":"B8CY71","id":"LON_HALOH","source_organism":{"taxId":"373903","scientificName":"Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562)","fullName":"Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562)"},"name":"Lon protease","description":["ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner"],"length":783,"sequence":"MDQEMVTKETEKYIELPLLASRGVVVFPHMVIPLLVGREKSIEALEKAMVKDKEIIILSQKDEKIEDPDPEDLYTIGTIAEVKQLVKLPNGMLKVVVEGIKRARIIDFIEIDEYFEVRAEILDQTVPEVDLEMKALMKAVLNKFQEYIKYNRNLPSETIMTVTNIEEPARFSDTIASHLELKFRQEQDLLEAISIKERLNKLLEIIKDEIEILKVEQKIQKKVRKQVEKTQKEYYLREQLKAIKEELDEDEEDDEIEEYRNKAEELDLPEKIREKVDKEIEKLKKTPSMSPEATVIRNYLDCVLDLPWNKVREEKIDLDEAKNVLDSEHYGLEDVKERILEYLAVRKLAPQKKSPILCLIGAPGVGKTSLGRSIARALGRDFVRLSLGGVRDEAEIRGHRRTYIGSRPGRIINAMREAGSKNPVFLLDEVDKMSSDFRGDPAAALLEVLDPEQNNEFTDHYLELPFDLSKVLFVTTANVAYPIPAPLLDRMEVIELPGYTEDEKVEIALRHLIPRILNEHGLTEDEIHFSSNSIYRIIREYTREAGVRNLERKLAAITRKVSKEIVEGRGRQARVTTQSIEKYLGVPKFKYEKAQKKDRVGVATGMAYTQTGGDILDIEVAVVPGKGKLTLTGSLGDVMKESARAALSYIRSKQEELGLSDNFHEEYDLHVHVPKGATPKDGPSAGITIASAIASALTGQPVKGKYAMTGEVTLRGRVLPVGGIKTKIMAARRAGLKDIIMPEENKKDFEEIPVKIKKDIRVNFVNHMDQVLDLILGGDEDEN","proteome":"UP000000719","gene":"lon","go_terms":[{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016887","name":"ATP hydrolysis activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004176","name":"ATP-dependent peptidase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004252","name":"serine-type endopeptidase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006508","name":"proteolysis","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0030163","name":"protein catabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0043565","name":"sequence-specific DNA binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"2f097c5f60e4d761110cc67d9e687e0ad163e8a5","counters":{"domain_architectures":30780,"entries":39,"isoforms":0,"proteomes":1,"sets":5,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":6,"ssf":3,"smart":2,"profile":2,"cdd":1,"pfam":4,"pirsf":1,"ncbifam":2,"panther":1,"hamap":1,"prints":1,"prosite":1,"interpro":14},"proteome":1,"taxonomy":1,"similar_proteins":30780}}}