{"metadata":{"accession":"B7UPF1","id":"NUDC_ECO27","source_organism":{"taxId":"574521","scientificName":"Escherichia coli O127:H6 (strain E2348/69 / EPEC)","fullName":"Escherichia coli O127:H6 (strain E2348/69 / EPEC)"},"name":"NAD-capped RNA hydrolase NudC","description":["mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates"],"length":257,"sequence":"MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQLQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE","proteome":"UP000008205","gene":"nudC","go_terms":[{"identifier":"GO:0016787","name":"hydrolase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0046872","name":"metal ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000210","name":"NAD+ diphosphatase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"3699a44c1f8bf9d98308f8700bb15e18a36a8aa4","counters":{"domain_architectures":5154,"entries":18,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":1,"pfam":2,"profile":1,"cdd":1,"hamap":1,"ncbifam":1,"panther":1,"prosite":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":5154}}}