{"metadata":{"accession":"B7N3J3","id":"B7N3J3_ECOLU","source_organism":{"taxId":"585056","scientificName":"Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)","fullName":"Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)"},"name":"Crossover junction endodeoxyribonuclease rusA","description":["Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC","Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC"],"length":122,"sequence":"MTERIEFVLPYSPTVNTYWRRRGSTYFVSKAGERYRRAVALIVRQQRLKLSLSGRLAIKIIAEPPDKRRRDLDNILKAPLDALTHAGLLMDDEQFDEINIVRGQPVSGGRLEIRITEVGVHE","proteome":null,"gene":"ECUMN_1327","go_terms":[{"identifier":"GO:0000287","name":"magnesium ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006281","name":"DNA repair","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0006310","name":"DNA recombination","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0008821","name":"crossover junction DNA endonuclease activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"51a6e3118f63bcc70816f9e3b12fbaee705e2bfd","counters":{"domain_architectures":6596,"entries":7,"isoforms":0,"proteomes":0,"sets":0,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pirsf":1,"pfam":1,"interpro":3},"proteome":0,"taxonomy":1,"similar_proteins":6596}}}