{"metadata":{"accession":"B7MNN4","id":"ISPH_ECO81","source_organism":{"taxId":"585397","scientificName":"Escherichia coli O81 (strain ED1a)","fullName":"Escherichia coli O81 (strain ED1a)"},"name":"4-hydroxy-3-methylbut-2-enyl diphosphate reductase","description":["Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis"],"length":316,"sequence":"MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDATDIQEEWVKEAKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD","proteome":null,"gene":"ispH","go_terms":[{"identifier":"GO:0046872","name":"metal ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051745","name":"4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0019288","name":"isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0050992","name":"dimethylallyl diphosphate biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"fcbea5256286b22a5f6231f48f5b4e45375830bf","counters":{"domain_architectures":23559,"entries":10,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cdd":1,"cathgene3d":2,"hamap":1,"ncbifam":3,"panther":1,"pfam":1,"interpro":1},"proteome":0,"taxonomy":1,"similar_proteins":23559}}}