{"metadata":{"accession":"B6HYI5","id":"B6HYI5_9GAMM","source_organism":{"taxId":"256325","scientificName":"Psychrobacter maritimus","fullName":"Psychrobacter maritimus"},"name":"HTH tetR-type domain-containing protein","description":["TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites"],"length":207,"sequence":"MAKLDKEQVIDNALILLNEVGIEGLTTRKLAQKIGVEQPTLYWHVKNKRALLDALAETILQKHHHHVLPLPNETWQDFLRNNAKSFRQALLMYRDGGKIHAGTRPSESQFETSEQQLQFLCDAGFSLSQAVYALSSIAHFTLGSVLETQEHQESQKEREKVETDTVAYPPLLTQAVAIMDSDNGDAAFLFVLDVMISGLETVLKSAK","proteome":null,"gene":"tetR","go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0045892","name":"negative regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003700","name":"DNA-binding transcription factor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0046677","name":"response to antibiotic","category":{"code":"P","name":"biological_process"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"bb9df0a8dcea275ef097e7769ed7a966a831eec3","counters":{"domain_architectures":29065,"entries":19,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"profile":1,"ssf":2,"pfam":2,"ncbifam":1,"panther":1,"prints":2,"prosite":1,"interpro":7},"proteome":0,"taxonomy":1,"similar_proteins":29065}}}