{"metadata":{"accession":"B4EPC1","id":"B4EPC1_BURCJ","source_organism":{"taxId":"216591","scientificName":"Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)","fullName":"Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)"},"name":"dihydrouracil dehydrogenase (NAD(+))","description":["Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT)"],"length":438,"sequence":"MADLRCTIAGITSPNPFWLASAPPTDKAYNVNRAFEAGWGGVVWKTLGLDPHVVNVSSRYGAVQWNGQRIAGLNNIELITDRPLDVNLREIAQVKRDWPDRALIVSLMVPCNERDWKWILPLVEDTGADAVELNFGCPHGMSERGMGAAVGQVPEYVEMVTRWVKEGTKLPCLVKLTPNISDIRMGSRAAYKGGADGVSLINTINSIVAVDLDQMAPMPTVDGKGTHGGYCGPAVKPIALNMVAEIARDPETPNLPISGIGGISSWRDAAEFMVLGAGSVQVCTAAMHYGFRIVSDLADGLSNWMDEKGYATLDDIRGRAVPNVTDWKYLNLKYDIKARIDQDRCIQCGLCHIACEDTSHQAITATKDGVRHFEVVDSACVGCNLCMHVCPVEQCITMERVDSGDYANWTTHPNNPASAEAGASAGAAAPDKHAKKAA","proteome":"UP000001035","gene":"BCAS0733","go_terms":[{"identifier":"GO:0016627","name":"oxidoreductase activity, acting on the CH-CH group of donors","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"876d31783ab46b2e5ca2da08862105471eecc90a","counters":{"domain_architectures":4468,"entries":15,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cdd":1,"pfam":2,"cathgene3d":2,"profile":1,"ncbifam":1,"panther":1,"prosite":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":4468}}}