{"metadata":{"accession":"B3T2V9","id":"B3T2V9_9ARCH","source_organism":{"taxId":"455564","scientificName":"uncultured marine crenarchaeote HF4000_ANIW93H17","fullName":"uncultured marine crenarchaeote HF4000_ANIW93H17"},"name":"Type 2 DNA topoisomerase 6 subunit A","description":["Relaxes both positive and negative superturns and exhibits a strong decatenase activity"],"length":365,"sequence":"MKKKPKKKVSEDKQSTLADLLRKHGAQIYDDLDKGNFPKFSIPSRSVSNIVYDKKIRQYILGANTAVRSSRNSSQLRSFTQLMWLAFFANRLTGQKKSSTLRDVYYSSQAFEVDFEDQAESDNIIVDLEAVLASPRESFHVFPEERSSVFGDLTIEYTVPGYQGKKTNLSDHPDGYAIGPSLTTAELIETSAEVVIAVEKGGLFTRFVEEQVDKKFKAIIVDTGGQAPRSTRTLLKRLHDELSLPVVILTDGDVYGEHIAMVIKSGSANAAHLRGLTVPDAKWVGVWATDIEKYKLPTIPMTESDIKRCHDLLKDPRYQEGIWKKELEVFLKIKRKAELEAFSKYGLTNITDKYLPHKLELAKSL","proteome":null,"gene":"top6A","go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005694","name":"chromosome","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006259","name":"DNA metabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003918","name":"DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006265","name":"DNA topological change","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"2bbc8485125458ebc79e2bcfff54696114431abd","counters":{"domain_architectures":4386,"entries":18,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"profile":1,"ssf":1,"pfam":2,"cdd":1,"ncbifam":1,"hamap":1,"panther":1,"prints":2,"interpro":6},"proteome":0,"taxonomy":1,"similar_proteins":4386}}}