{"metadata":{"accession":"B3RKM2","id":"B3RKM2_TRIAD","source_organism":{"taxId":"10228","scientificName":"Trichoplax adhaerens","fullName":"Trichoplax adhaerens"},"name":"AP complex subunit sigma","description":["Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal"],"length":141,"sequence":"MIKFILLVNKDGQSRLSRYYHNILGEERENLERETIQKCLPRSKKECSFLEYQNMMLIYRRYMSLFFIVGVDSDENELSILELIQNLVETFDRYFNDVSELDITMNVEKAYMILDEMILNGHIIETSKNRILAPIYATENN","proteome":"UP000009022","gene":"TRIADDRAFT_18389","go_terms":[{"identifier":"GO:0015031","name":"protein transport","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"06d32c800fac36020d03f379936b1bd62ff88561","counters":{"domain_architectures":27458,"entries":9,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"pfam":1,"ssf":1,"cathgene3d":1,"cdd":1,"pirsf":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":27458}}}