{"metadata":{"accession":"B3DM26","id":"B3DM26_XENTR","source_organism":{"taxId":"8364","scientificName":"Xenopus tropicalis","fullName":"Xenopus tropicalis (Western clawed frog)"},"name":"Homeobox protein vex1","description":["Transcriptional repressor. Acts in a ventral signaling pathway downstream of bmp4 to antagonize the Spemann organizer and ventrally pattern the embryonic mesoderm. Represses transcription of the dorsal genes gsc and otx2"],"length":282,"sequence":"MEKRPYSVAWLSESSQRKPLCTNVDLLGYKSGNPDLPPNREYNVSLPSRVILPTPDYREKENYCGRNVHNGERSPPVRDQLHFHPAPQELTTSRRTSIEVSAESSTDQRVIGMTDTNKKTKSVCDEDAASRARTKFTAEQLEELEKSFKENRYIGSSEKRRLSKVLKLSENQIKTWFQNRRMKFKRQTQDARVEAFFSGLYLPYYGYPDLPTPGYSVQSEFPVLAPQTMAASSIPFGPLHSTVMSPGLHPAIPSANLGSYPCSSMLVRPILNEPTRQRYSPY","proteome":"UP000008143","gene":"ventx3.2","go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000981","name":"DNA-binding transcription factor activity, RNA polymerase II-specific","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}}],"protein_evidence":2,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"1cca9db9652b5e6e0313f2eed7be72cec278d12f","counters":{"domain_architectures":145457,"entries":12,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"profile":1,"smart":1,"ssf":1,"pfam":1,"cdd":1,"panther":1,"prosite":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":145457}}}