{"metadata":{"accession":"A8F821","id":"THIC_PSELT","source_organism":{"taxId":"416591","scientificName":"Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO)","fullName":"Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO)"},"name":"Phosphomethylpyrimidine synthase","description":["Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction"],"length":424,"sequence":"MTQMEIAQKGTSSEEMKRVAEYEEMNLEVIRQKLAYGKAVLPKNKLHKIEKPMIVGEGFTVKVNANIGTSQAFFSLEEEKEKARVAIEYGADSLMVLSTWGDLKEIRKAIIDLSAVPVGSVPIYDSAMKSYQLKKNVVDFSEKDFLNMVISHAEDGIDFMTIHAGITKKVLEHVKNSGRILKVVSRGGAIIAGWMIKNNKENPFYEYFDELLDIAKDYDITLSLGDGMRPGTVLDASDVQQFEELFVMRELVEKAREKGVQVMLEGPGHIPLNEVELNVKLMKKIGEDAPIFLLGPLPTDRAMGYDHIACAIGGALAGYYGADFLCYVTPSEHISLPTIEDVREGVIASKIAAAIADLARGNRKAWWLEKQMALSRKNFNWEEMFKLSLGKDLARKKYKERPYLHEGCSMCGPFCAIKIVEEFF","proteome":"UP000002016","gene":"thiC","go_terms":[{"identifier":"GO:0051536","name":"iron-sulfur cluster binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009228","name":"thiamine biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016830","name":"carbon-carbon lyase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"5d631a44aea4949be807789b575e63b04da8956f","counters":{"domain_architectures":5552,"entries":12,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"pfam":1,"cathgene3d":1,"panther":1,"ncbifam":2,"hamap":1,"sfld":3,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":5552}}}