{"metadata":{"accession":"A7ZK99","id":"A7ZK99_ECO24","source_organism":{"taxId":"331111","scientificName":"Escherichia coli O139:H28 (strain E24377A / ETEC)","fullName":"Escherichia coli O139:H28 (strain E24377A / ETEC)"},"name":"TorCAD operon transcriptional regulatory protein TorR","description":["Member of the two-component regulatory system TorS/TorR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Phosphorylated TorR activates the transcription of the torCAD operon by binding to four decameric boxes located in the torCAD promoter. Box1, 2 and 4 contain the DNA sequence 5'-CTGTTCATAT-3' and box3 contains the DNA sequence 5'-CCGTTCATCC-3'. Phosphorylated as well as unphosphorylated TorR negatively regulates its own expression by binding to box1 and 2"],"length":230,"sequence":"MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQNQPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTKPLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTRAEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQHGEGYFLAADVC","proteome":"UP000001122","gene":"torR","go_terms":[{"identifier":"GO:0000160","name":"phosphorelay signal transduction system","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0000976","name":"transcription cis-regulatory region binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"214263e87a1ba73528c547c1c5657a9093191d60","counters":{"domain_architectures":293517,"entries":19,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"smart":2,"cdd":2,"ssf":1,"cathgene3d":3,"profile":2,"pfam":2,"ncbifam":1,"panther":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":293517}}}