{"metadata":{"accession":"A7MJ58","id":"ISPF_CROS8","source_organism":{"taxId":"290339","scientificName":"Cronobacter sakazakii (strain ATCC BAA-894)","fullName":"Cronobacter sakazakii (strain ATCC BAA-894)"},"name":"2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase","description":["Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)"],"length":159,"sequence":"MRIGHGFDVHAFGGTGPIILGGVRIPYEQGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMAPHIPQMRVFIAEDLGCHMDQVNVKATTTEKLGFTGRGEGIACEAVALLMKAGA","proteome":"UP000000260","gene":"ispF","go_terms":[{"identifier":"GO:0008685","name":"2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016114","name":"terpenoid biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"4806cfc55513dcfafc7c50c91b7c811c37f0503d","counters":{"domain_architectures":17724,"entries":11,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"cdd":1,"pfam":1,"panther":1,"hamap":1,"ncbifam":1,"prosite":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":17724}}}