{"metadata":{"accession":"A6MN33","id":"A6MN33_EPTFU","source_organism":{"taxId":"29078","scientificName":"Eptesicus fuscus","fullName":"Eptesicus fuscus (Big brown bat)"},"name":"Beta-2 adrenergic receptor","description":["Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine"],"length":214,"sequence":"FGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARMVILMVWIVSGLTSFLPIQMHWYRATHDEAIKCYAKDTCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKRQLQRIDKFAGRFHAQNLSQVEDGRXGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLI","proteome":null,"gene":"ADRB2","go_terms":[{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0004930","name":"G protein-coupled receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007186","name":"G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0004941","name":"beta2-adrenergic receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006940","name":"regulation of smooth muscle contraction","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0007189","name":"adenylate cyclase-activating G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0097746","name":"blood vessel diameter maintenance","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":true,"in_alphafold":false,"in_bfvd":false,"ida_accession":"587fa3dbe4504dc051049f3cca904dd9ab631b87","counters":{"domain_architectures":394800,"entries":11,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"profile":1,"ssf":1,"pfam":1,"panther":1,"prosite":1,"prints":2,"interpro":3},"proteome":0,"taxonomy":1,"similar_proteins":394800}}}