{"metadata":{"accession":"A5PJZ1","id":"SCMC1_BOVIN","source_organism":{"taxId":"9913","scientificName":"Bos taurus","fullName":"Bos taurus (Bovine)"},"name":"Mitochondrial adenyl nucleotide antiporter SLC25A24","description":["Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool, could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates"],"length":477,"sequence":"MLRWLRGFVLPTAACQDVEPPTRYETLFQKLDRNGDGVVDISELQEGLKSLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQILGLTISEQQAELILQSIDADGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGVAGAVSRTSTAPLDRLKVMMQVHGSKSAKMNIYGGFQQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFVSGSMAGATAQTFIYPMEVLKTRLAVGKTGQYSGMFDCAKKILKYEGMGAFYKGYVPNLLGIIPYAGIDLAVYELLKSHWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMIEKSPQLNMVGLFRRILSKEGLPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK","proteome":"UP000009136","gene":"SLC25A24","go_terms":[{"identifier":"GO:0005509","name":"calcium ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005743","name":"mitochondrial inner membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0055085","name":"transmembrane transport","category":{"code":"P","name":"biological_process"}}],"protein_evidence":2,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"70f879a8b3542c2ee14c96daedb06a8cc75e3ef3","counters":{"domain_architectures":4406,"entries":20,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"profile":2,"cathgene3d":2,"smart":1,"pfam":2,"panther":1,"prints":2,"prosite":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":4406}}}