{"metadata":{"accession":"A5IVE2","id":"HSSR_STAA9","source_organism":{"taxId":"359786","scientificName":"Staphylococcus aureus (strain JH9)","fullName":"Staphylococcus aureus (strain JH9)"},"name":"Heme response regulator HssR","description":["Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity)"],"length":224,"sequence":"MVQCLVVDDDPRILNYIASHLQTEHIDAYTQPSGEAALKLLEKQRVDIAVVDIMMDGMDGFQLCNTLKNDYDIPVIMLTARDALSDKERAFISGTDDYVTKPFEVKELIFRIRAVLRRYNINSNSEMTIGNLTLNQSYLELQVSNKTMTLPNKEFQLLFMLAARPKQIFTREQIIEKIWGYDYEGDERTVDVHIKRLRQRLKKLNATLTIETVRGQGYKVENHV","proteome":null,"gene":"hssR","go_terms":[{"identifier":"GO:0000160","name":"phosphorelay signal transduction system","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0000976","name":"transcription cis-regulatory region binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"214263e87a1ba73528c547c1c5657a9093191d60","counters":{"domain_architectures":293517,"entries":18,"isoforms":0,"proteomes":0,"sets":4,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"smart":2,"ssf":1,"profile":2,"cdd":2,"pfam":2,"panther":1,"interpro":5},"proteome":0,"taxonomy":1,"similar_proteins":293517}}}