{"metadata":{"accession":"A4H7F2","id":"A4H7F2_LEIBR","source_organism":{"taxId":"5660","scientificName":"Leishmania braziliensis","fullName":"Leishmania braziliensis"},"name":"Squalene monooxygenase","description":["Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis"],"length":569,"sequence":"MLYFFATVLCAFGTLLLLNRTLSRLRVSPARTSYDYDVIIVGGSIAGPVMAKVLSDQGRKVLMVERTLFTKPDRIVGELLQPGGLNALKEVGMKECAESIGMPCHGYLVVDLKGDQVDLPYRKGASGVSFHFGDFVQGLRSYVFHNCKKNVTMIEGTVNAILTEGFSFSERAYGVEYTVAEKYEVPANPFREDPPKADPMVRTVRRVATAPLVVMCDGGMSKWKSRYQHYTPASANHSNFVGLVLKKVRLPKEQRGTVFFGKTGPILSYRLDDSELRILVDYNKPMLPSLEKQSEWLIQDVAPRLPEHMREEFIRVSKDTKSLRSMPVALYPPAFPCIKGYVGIGDHANQRHPLTGGGMTCCFRDAIRLANSLKGIPSLRSANQDEMAAIEDTVQSAILNYVRFRYTHSCCINLLSWALYSVFSTPALRDACFDYFVCGGECVSGPMDLLAGLDPSLGALIFHYYGVVLYSVANVIMGVGVHNGSGKQLSDLEKLMNVASFFVDWERMKHAAYLLGKSTKIALPLVKNEFFSMWRFVDPTSPLANISKRIKMMIYARQLNGKQRKPVGI","proteome":"UP000007258","gene":"LBRM_13_1480","go_terms":[{"identifier":"GO:0004506","name":"squalene monooxygenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016126","name":"sterol biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0050660","name":"flavin adenine dinucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"7480fefb765e2b921571ded7344e6e5d708381d6","counters":{"domain_architectures":2362,"entries":8,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"panther":1,"pfam":1,"prints":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":2362}}}