{"metadata":{"accession":"A0QWT3","id":"METK_MYCS2","source_organism":{"taxId":"246196","scientificName":"Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)","fullName":"Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)"},"name":"S-adenosylmethionine synthase","description":["Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme"],"length":399,"sequence":"MSKGRLFTSESVTEGHPDKICDAISDSVLDALLEQDPKSRVAVETLVTTGQVHVAGEVTTTAYADIPKIVRDRILDIGYDSSTKGFDGASCGVNVAIGAQSPDIAQGVDTAHETRVEGKADPLDLQGAGDQGLMFGYAIGDTPELMPLPIALAHRLARRLTEVRKNGVLDYLRPDGKTQVTIQYDGTTPVRLDTVVLSTQHADGIDLEGTLTPDIREKVVNTVLADLGHETLDTSDYRLLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGSETVDPAKIEKAIGEVFDLRPAAIVRDLDLLRPIYAPTAAYGHFGRTDIELPWEQTNKVDDLKSAI","proteome":"UP000000757","gene":"metK","go_terms":[{"identifier":"GO:0004478","name":"methionine adenosyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006556","name":"S-adenosylmethionine biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"19eaff5c12f42b31629adc7742ec6ffb3fe068a7","counters":{"domain_architectures":35253,"entries":18,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"pfam":3,"cathgene3d":1,"cdd":1,"pirsf":1,"hamap":1,"panther":1,"ncbifam":1,"prosite":2,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":35253}}}