{"metadata":{"accession":"A0AAA9ST80","id":"A0AAA9ST80_BOVIN","source_organism":{"taxId":"9913","scientificName":"Bos taurus","fullName":"Bos taurus (Bovine)"},"name":"Hexosyltransferase","description":["Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity"],"length":480,"sequence":"STPCLSPGRDFDSRLADQLALFPQWKSNHYDVVVGVLSARNNHQLRNVIRSTWLKHLLQHPALSQRVLVKFIIGAHGCTVPVEDREDPYSCKLLNITNPVLNQEIEAFSLLEDTSSGLSEDRVVSVSFRVLYPIVITSLGVFYDAGDVGFQRNITVKLYQAEQEEALFSARFSPPSCGVQVNKLWYKPVEQFILPESFEGTIVWESQDLQGLVSRNLHKVTVNDGGGVLRVVTTGEGALPHEFMEGVEGVAGGFIYTIQEGDALLKTLHSRPRRLLDHIHNLHEEDALLKEESSLYDDIVFVDVVDTYRNVPAKLLNFYRWTVETTSFDLLLKTDDDCYIDLEAVFNRIALKNLDGPNFWWGNFRLNWAVDRTGKWQELEYPSPAYPAFACGSGYVISRDIVHWLAGNSGRLKTYQGEDVSMGIWMAAIGPKRYQDSLWLCEKTCEPGMLSSPQYSPQELAQLWRLKELCGDPCRCEGRG","proteome":"UP000009136","gene":"B3GALNT2","go_terms":[{"identifier":"GO:0016758","name":"hexosyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009101","name":"glycoprotein biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"ad501d98169c72b7fb1ce175efd5c4d3c278e4fd","counters":{"domain_architectures":27846,"entries":4,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"panther":1,"pfam":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":27846}}}