{"metadata":{"accession":"A0AA97J378","id":"A0AA97J378_EUBMA","source_organism":{"taxId":"481883","scientificName":"Eublepharis macularius","fullName":"Eublepharis macularius (Leopard gecko)"},"name":"Multifunctional fusion protein","description":["Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation","Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays"],"length":489,"sequence":"MNLAEICDNAKKGREYALLGNYDSSMVYYQGVIQQIQRHCQSIRDPTLKGKWQQVRQELLEEFEQVKSIVSTLESFKVDKPTDIPVSYQDEPFRDPSVWPPPVPAEHRAPPQIKRPNREVKPLRRESPGLQRGPVGRAQPISKNEKPASSREREAKAKGKDEKGKKISQDGAGDNDIQKFDGGGYDKDLVEALERDIVSRNLSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNISSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDEHEASRRVKSELLVQMDGVGGALENDDPSRMVMVLAATNFPWDIDEALRRRLEKRIYIPLPTAKGRAELLKINLREVELDPDINLEEIAEKIEGYSGADITNVCRDASLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFDLALKKISKSVSAADLEKYDKWMSEFGSA","proteome":"UP001190640","gene":"KATNAL1","go_terms":[{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016887","name":"ATP hydrolysis activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008568","name":"microtubule severing ATPase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051013","name":"microtubule severing","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005874","name":"microtubule","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0008017","name":"microtubule binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"487a925a16d059a03672cfa302b552bf5c6edb50","counters":{"domain_architectures":2323,"entries":26,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"cdd":2,"pfam":4,"ssf":1,"smart":1,"hamap":2,"panther":1,"prosite":1,"interpro":11},"proteome":1,"taxonomy":1,"similar_proteins":2323}}}