{"metadata":{"accession":"A0AA88T2I3","id":"A0AA88T2I3_TACVA","source_organism":{"taxId":"175792","scientificName":"Tachysurus vachellii","fullName":"Tachysurus vachellii (Darkbarbel catfish)"},"name":"Histone H4","description":["Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling"],"length":103,"sequence":"MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG","proteome":"UP001187315","gene":"Q7C36_004262","go_terms":[{"identifier":"GO:0046982","name":"protein heterodimerization activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0030527","name":"structural constituent of chromatin","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000786","name":"nucleosome","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"cc5656b4730552f32eca61d967a095cc120b3796","counters":{"domain_architectures":10290,"entries":14,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"smart":2,"cdd":1,"pfam":1,"panther":1,"prosite":1,"prints":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":10290}}}