{"metadata":{"accession":"A0AA41NI79","id":"A0AA41NI79_SCICA","source_organism":{"taxId":"30640","scientificName":"Sciurus carolinensis","fullName":"Sciurus carolinensis (Eastern gray squirrel)"},"name":"Delta(24)-sterol reductase","description":["Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis"],"length":516,"sequence":"MEPAVSLAVCALLFLLWVRVKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYSVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVSMGQVTALLTSIGWTLPVLPELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIVPAKKYVKLRFEPVRGLETICEKFTRESQRLENHFVEGLLYSLDEAVIMTGVMTDEAEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLRQALLTFHNDIHVYPIWLCPFILPSQPGLVHPKGDEAELYVDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLRKQLGCQDAFPEVYDKICKAARH","proteome":"UP001166674","gene":"SUZIE_210195","go_terms":[{"identifier":"GO:0050660","name":"flavin adenine dinucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0071949","name":"FAD binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"4fd365ad8e65dd9fb351a4ac2837536f547eb4d3","counters":{"domain_architectures":41883,"entries":10,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"profile":1,"pfam":1,"cathgene3d":1,"panther":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":41883}}}