{"metadata":{"accession":"A0A9W2VPA4","id":"A0A9W2VPA4_PANPR","source_organism":{"taxId":"9691","scientificName":"Panthera pardus","fullName":"Panthera pardus (Leopard)"},"name":"Triadin","description":["Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact. Required for normal skeletal muscle strength. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats"],"length":712,"sequence":"MTEITAEGNASTTTTVIDSKNGSVPKSPGKVLKRTVTEDIVTTFSSPAAWLLVIALIITWSAVAVVMFDLVDYKNFSASSISKIGSDPLKLIHDAVEETTDWVYGFFSLLSDIISSEGDEEDDDGDEDTDKGEIEEPPLKQKEIHKDKTEKQEKPERKIVPKVTHKEKPKEKEKAEKKATHKEKIEKKEKPETKTVAKEERKTKTEEKIKKEVKGGKQEKVKQTAAKVKEVQRPSPKPKEKEGKENAAVSKHEQKDQYAFCRYMIDMFVRGDLKPGQSPAVPPPLPTERASRPTPASPTPEGKEEEEKKKAEKKVTSETKKKEKEAVKKKTDKETAVDVKKKEPGKAPETKQGTTKVAAQATAKKDEKKEDSKKTKTTIEEQPKGKKQEKKEKHVEPAKSSKKEHSAPSEKQIKAKTERAKEEAGAASTKKAVPGKKEEKTTKTVEQEIKKEKSRKTSSVLKDKEPIKGKEVKLPVSLKEKEPEIKKEEKIPKAGKEVKPKPPQPQVKKEEKPESQVKKETKPEQDRAKPEKTVSHGKPEEKVVKQVKATTIEKPVKLKPTKKAEHQEKESPSIKTDKTKPTTKETSEIIESGKKKIEKPEKESKEKTEMKHLKEEKVSTRKESLQSHNVTKAEKPARVSREDLEDVPASKKAEEAEDVYSTKKQKSPISFFQCVYLDGYNGYGFQFPVTPAHHPGESSGQRSSPGQKQQGQ","proteome":"UP001165780","gene":"TRDN","go_terms":[{"identifier":"GO:0005102","name":"signaling receptor binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0016529","name":"sarcoplasmic reticulum","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"af6f1641e7a9309ba58401a49c3075e7ce16089a","counters":{"domain_architectures":2764,"entries":4,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"panther":1,"pfam":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":2764}}}