{"metadata":{"accession":"A0A9L0JIG1","id":"A0A9L0JIG1_EQUAS","source_organism":{"taxId":"9793","scientificName":"Equus asinus","fullName":"Equus asinus (Donkey)"},"name":"Mediator of RNA polymerase II transcription subunit 22","description":["Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors"],"length":200,"sequence":"MAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLITLRDEISIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDLDTDSTDGLSAPLLASPEPSAGPLQAAAPAHSHAGGPGPTEHA","proteome":"UP000694387","gene":"MED22","go_terms":[{"identifier":"GO:0003712","name":"transcription coregulator activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006357","name":"regulation of transcription by RNA polymerase II","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016592","name":"mediator complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"54e27fb41ee85053173af7d3fefd198ef88c8a99","counters":{"domain_architectures":3758,"entries":3,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"panther":1,"pfam":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":3758}}}