{"metadata":{"accession":"A0A9F7TKM6","id":"A0A9F7TKM6_ICTPU","source_organism":{"taxId":"7998","scientificName":"Ictalurus punctatus","fullName":"Ictalurus punctatus (Channel catfish)"},"name":"Mitochondrial 2-oxodicarboxylate carrier","description":["Transports dicarboxylates across the inner membranes of mitochondria by a counter-exchange mechanism. Can transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate (2-aminohexanedioate), oxaloacetate, and citrate. Plays a central role in catabolism of lysine, hydroxylysine, and tryptophan, by transporting common metabolite intermediates (such as 2-oxoadipate) into the mitochondria, where it is converted into acetyl-CoA and can enter the citric acid (TCA) cycle"],"length":283,"sequence":"MWGKETRGLVEICLMHPLDVVKTRFQIQRGVSDPNSYKGLEDCFRTIFHKEGVHGFYKGILPPILAETPKRAVKFFTFEQYKNLLSYTTLSQGLALSLAGLGSGLTEALVVNPFEVVKVSLQADRNSFKVQPSTFTQARMIINSDGFGLRGLNKGLTSTLGRHGVFNMIYFGFYFNVKNTLPASQDPRLEFMRKFTIGLLSGTISSCVNIPFDVAKSRIQGPQPVPGEIKYRSCFQTMTLVYREEGYLALYKGLIPKIMRLGPGGAVMLLVYEYVSSWLQRNW","proteome":"UP000221080","gene":"slc25a21","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"e037822792ef5f5d7967370632f8bf737b916266","counters":{"domain_architectures":140476,"entries":8,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"profile":1,"cathgene3d":1,"ssf":1,"pfam":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":140476}}}