{"metadata":{"accession":"A0A9F2QWB6","id":"A0A9F2QWB6_PYTBI","source_organism":{"taxId":"176946","scientificName":"Python bivittatus","fullName":"Python bivittatus (Burmese python)"},"name":"E3 ubiquitin-protein ligase E3D","description":["E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Independently of its E3 ubiquitin-protein ligase activity, acts as an inhibitor of CPSF3 endonuclease activity by blocking CPSF3 active site"],"length":385,"sequence":"MEATLFLEIRERMQSGSLIIRELHPESWPVDIAVMPSLVELKSGKACKAFSLPPGVAIVPSSCRGLQYLPGEGLHLRLLVQVDFSAKLMPAVGDGLKSKKSCTFYCQSCGESVINNRTFLRVLSLPFENWNDLVEEWCCHPNPFNDSLLHPQNDDCFLGHNYLMINSRSELSGTESGILYSEDEWATSCESPSNSQANSTVICKRCKTLLGEAMPSGVIKYYFTELLVQPSEDSFHVIPRSSFIRSVIARCFMELAFSRSTFRFSIQGMDGTVYILIWILNCDTLMVETSGNPASNNVFTLLEPELSSSLRPAEIHKAVKVLYHPCTENRNKDLVDSWGEDIGVSSLTFPSKTCLELLLILSQSNASLPPSLRWMNSFQVAFLKL","proteome":"UP000695026","gene":"UBE3D","go_terms":null,"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"b9b613a3502898c2e8f146ca4f1002d6a7ee4c1a","counters":{"domain_architectures":3753,"entries":3,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"pfam":1,"panther":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":3753}}}