{"metadata":{"accession":"A0A977K7W4","id":"A0A977K7W4_BERSP","source_organism":{"taxId":"88663","scientificName":"Beryx splendens","fullName":"Beryx splendens (Splendid alfonsino)"},"name":"Elongation of very long chain fatty acids protein 4","description":["Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators"],"length":320,"sequence":"MEIVTHLINDTIEFYKWSLTIADKRVEKWPLMDNPLPTLAISTSYLLFLWLGPKYMKNREPFQLRKTLIVYNFSMVFLNFFICKELFMAARAASYSYICQPVDYSEDPNEVRVAGALWWYFISKGIEYLDTVFFILRKKFNQVSFLHVYHHCTMFTLWWIGIKWVAGGQSFFGAHMNAAIHVLMYLYYGLASCGPKIQKYLWWKKYLTIIQMIQFHVTIGHTALSLYVDCDFPHWMHYSLICYAITFIVLFGNFYYQTYRRQQPRRDASSSSSKPGKALSNGTLNGLSKAANGVAVTGGKEEKPQENSGRRKRKGRAKRD","proteome":null,"gene":"elovl4a","go_terms":[{"identifier":"GO:0009922","name":"fatty acid elongase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0019367","name":"fatty acid elongation, saturated fatty acid","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0042761","name":"very long-chain fatty acid biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005783","name":"endoplasmic reticulum","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":2,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"726b44df556ad17af08cf1eeb76a7efce6e198bf","counters":{"domain_architectures":25966,"entries":7,"isoforms":0,"proteomes":0,"sets":0,"structures":0,"taxa":1,"dbEntries":{"hamap":1,"panther":1,"pfam":1,"prosite":1,"interpro":3},"proteome":0,"taxonomy":1,"similar_proteins":25966}}}