{"metadata":{"accession":"A0A974HVP1","id":"A0A974HVP1_XENLA","source_organism":{"taxId":"8355","scientificName":"Xenopus laevis","fullName":"Xenopus laevis (African clawed frog)"},"name":"SAM pointed domain-containing Ets transcription factor","description":["May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter"],"length":317,"sequence":"MGSNSANLPSVTHSRLALQDSTLTSLDKASDEGAPGYYLPFCDMLYAGEGGSWAPKGLMQVVHRGEGTKEPEQCPVIDSQGLHHELEYQTSLHLEDHSLEQMQTMVVGEVLKDIETACKLLNISADPMEWSAGNVQKWILWTEHQYRLPQVGRSFQELTGKDLCALSEENFRERSPLCGDVLYAHLDIWKSAAWMKEKTGPGELRYCGGSGVVGECWADTEVDSSGSGQPIHLWQFLKELLLKPHSYGRSIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDVSQRLVYQFVHPL","proteome":null,"gene":"spdef.S","go_terms":[{"identifier":"GO:0043565","name":"sequence-specific DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003700","name":"DNA-binding transcription factor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0006357","name":"regulation of transcription by RNA polymerase II","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"522927238307a85066168b858327df5283cc4088","counters":{"domain_architectures":10817,"entries":21,"isoforms":0,"proteomes":0,"sets":3,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cathgene3d":2,"profile":2,"smart":2,"pfam":2,"cdd":1,"panther":1,"prints":1,"prosite":2,"interpro":6},"proteome":0,"taxonomy":1,"similar_proteins":10817}}}