{"metadata":{"accession":"A0A8U0W7U7","id":"A0A8U0W7U7_9MUSC","source_organism":{"taxId":"7396","scientificName":"Glossina fuscipes","fullName":"Glossina fuscipes"},"name":"Rho GDP-dissociation inhibitor 3","description":["Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP"],"length":203,"sequence":"MSIEITNEVELHDEELQDANYQPPPEKTIEEIMAADQEDESLRRYKEILLGAAQAEKIVVDMNDQRKVLVKKLALVVDGRKDMELDLTGDLSQLKKQVFVIKEGVQYKVRIDFIVQREIVHGLKYVQKTYRLGVPDLIVDKMTHMVGSYPPKKEIQCYITPSEEAPSGLMARGTYSVSSLFTDDDKHIHLKWDWTFEIKKDWE","proteome":"UP000092443","gene":"LOC119632351","go_terms":[{"identifier":"GO:0005094","name":"Rho GDP-dissociation inhibitor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007266","name":"Rho protein signal transduction","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"a047cc2a90c5a451e918e7e7fd5504acdc6be23f","counters":{"domain_architectures":7110,"entries":8,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"pfam":1,"ssf":1,"cathgene3d":1,"panther":1,"prints":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":7110}}}