{"metadata":{"accession":"A0A8U0MQD4","id":"A0A8U0MQD4_MUSPF","source_organism":{"taxId":"9669","scientificName":"Mustela putorius furo","fullName":"Mustela putorius furo (European domestic ferret)"},"name":"Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase","description":["Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect"],"length":493,"sequence":"MPVPTEGTPPRLSGTPVPVPAYFRHAEPGFSLKRPGGLSRSLPPRPPAKGSIPVSRLFPPRTPGWHQPQPRRVSFRSKASETLQSPSYDPSRPESFFQQSFQRLGRLGHGSYGEVFKVRSKEDGRLYAIKRSMSPFRGPKDRARKLAEVGGHEKVGQHPRCVRLEQAWEEGGILYLQTELCGPSLQQHSEAWGTGLPEAQVWGYLRDTLLALAHLHGQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGTSGAGEAQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLTMMLEPDPKLRATASALLALPMLRRPRPWSVLWYVAADALSRGWALWQALLSLLCWLWHGLAHPASWLQPPSPPATPPGSPPCSLLLHSSLSSSWDDDSVGLSLSPEAVLARAAGNTSTPRNGSPAPRNRDALDLSDIDSEPPRGSFPAFEPRNLLSLFEDSLGPT","proteome":"UP000000715","gene":"PKMYT1","go_terms":[{"identifier":"GO:0004672","name":"protein kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006468","name":"protein phosphorylation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"726173b0dde7bbc50c5d845a39c992d18faf18f3","counters":{"domain_architectures":887312,"entries":15,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"cdd":1,"ssf":1,"pfam":1,"smart":1,"profile":1,"panther":1,"prosite":2,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":887312}}}