{"metadata":{"accession":"A0A8J4WGY0","id":"A0A8J4WGY0_9STRA","source_organism":{"taxId":"1284355","scientificName":"Phytophthora kernoviae 00238/432","fullName":"Phytophthora kernoviae 00238/432"},"name":"Multifunctional fusion protein","description":["Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration","Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration","Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX"],"length":805,"sequence":"MGRVIGDGGCFFQVVDIAVRPDQQGRGYGKLIMSEIMNYLREHVPARGLVSLLADVPADRLYAQFGFAYTRHEVTAIVREPSKVEMEHERLRVVQGDLLNPDQVADFTAGQEAVVSAYGPKFGSEEEMLEVTRSLIEGVRRSKAGRLVVVGGAGSLITDSGEMLMDTPGFPEEVKPLAKAHLDAYNLIEASDIHWTYMSPAATITTGRRTGLFRVGMNRVITDDLGESSISVGDFAAALVDELDDPQFIQSRFTMRAVDEHTIHKLGIPAASLMENAGKAIAEEVIRVCREVWKEGVGRSPEQQGGRNEGNRERAHTGPGDRQGHGGDIIADSALVMEQPGDQQWYVLIGKGNNGGDGLVAARHLVEAGLGVTLVYADAPDALRGEAAVQRDAAAQLGIPALVHGREAVDFSRCTGIVDALLGTGSSGAPRGAYAALIAAANDSGKPIVSADVPSGLNADTGEVYEPCIQARVTVCLALLKRGLVQYPGASAAGRIVVRSIGIPARLAPEHGPSVRLLTDEVLRGALRVDTGRLRAPDGHKGTYGHVLLAAGSLPMSGAGLLSAKSALRAGCGLATWALPAALLPHVIGTVPELMLAAAADGDSGEWNAASADAVLRLAESRDVLATGPGLGRFKGDTDWLRRLWQHTDRPLVIDADALNMLADAGPTGPRDWGKRSAATILTPHPGEMGRLLGMSTPEVQRDRIGHAARYAREQGVTLVLKGARTVIATPSGEAYINTTGHAGMATGGAGDVLTGIIAGLLAQGLSAEQAAAFGVFLHGQAAERAALLRGDPASLLAGDIMDAL","proteome":null,"gene":"G195_001957","go_terms":[{"identifier":"GO:0016747","name":"acyltransferase activity, transferring groups other than amino-acyl groups","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016836","name":"hydro-lyase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"68ae653ffbbc21dd07cdc639256fb369a851561e","counters":{"domain_architectures":1,"entries":32,"isoforms":0,"proteomes":0,"sets":5,"structures":0,"taxa":1,"dbEntries":{"cdd":2,"cathgene3d":4,"profile":3,"ssf":4,"pfam":4,"hamap":2,"panther":1,"ncbifam":2,"prosite":1,"interpro":9},"proteome":0,"taxonomy":1,"similar_proteins":1}}}