{"metadata":{"accession":"A0A8I3RS67","id":"A0A8I3RS67_CANLF","source_organism":{"taxId":"9615","scientificName":"Canis lupus familiaris","fullName":"Canis lupus familiaris (Dog)"},"name":"Activating signal cointegrator 1 complex subunit 1","description":["Plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction"],"length":355,"sequence":"MEVLRPQLVRIGGRIYRKNPIQEQTYQHEEEDEDFYQGFVECAEDPCDAYEVVQTQQGFRCTVKAPSLLYKHIVGKRGDTRKKLEVETKTSISIPKPGQEGEIVITGQHRSGVISARTRIDVLLLTFRRKQPFTHFLAFFLNEAEVQERFLKFQEEVLEKCSMDHGVDSTIFQNPKKLHLTIGMLVLLSEQEIQQTCEMLQQCKEEFIDDISGGKPLEVEMAGIEYMNDDPGMVDVLYAKVHMKDGSNRLQELVDRVLERFQASGLIVKEWNSVKLHATVMNTLFRKDPNGRYNLYTADGKYIFKERESFDGRNILKLFENFYFGTLKLNSIHISQRFTVDSFGNYASCGQIDFS","proteome":"UP000805418","gene":"ASCC1","go_terms":[{"identifier":"GO:0003723","name":"RNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003676","name":"nucleic acid binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"879a94808d9f2934635bd9106b371e1a86674277","counters":{"domain_architectures":2453,"entries":18,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"smart":1,"profile":1,"cdd":1,"pfam":2,"cathgene3d":2,"panther":1,"pirsf":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":2453}}}