{"metadata":{"accession":"A0A8I3NLX3","id":"A0A8I3NLX3_CANLF","source_organism":{"taxId":"9615","scientificName":"Canis lupus familiaris","fullName":"Canis lupus familiaris (Dog)"},"name":"Relaxin receptor 1","description":["Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP"],"length":679,"sequence":"MTSGPVFFYILILGKYLVGSVPMQCVCRGLEVDCDETNLRAVPSVSSNVTLMSLRWNLIRKLPPDGFRKYHNLQKLCLQNNKIRSIPIYAFRGLHSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPLTFYGLNSLILLALMNNVLTHLPDKPLCQYMPRLHWLDLEDNHIHNLRNLTFISCGNLTVLVMRKNKINHLNENTFAPLQKLAELDLGSNKIENLPPQVFKDLKELSQLNLSYNPIQKIQADQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLANIIQRVFVWVVSAVTCFGNIFVICMRSHIRSENKLHAMSIISLCCADCLMGIYLFVIGAFDLKFRGEYNKHAQLWMDSIHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCLRPRKCRTITVLILIWTSGFIVALIPLTNKEFFKNYYGTNGVCFPLHSEDIESTGAQIYSVAIFLGVNLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVLKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHQFWYNYRQRRSIDSKGSQKTYAPSFIWVEMWPLQEMPPELIKPALFTDPCELSLISQSTRLNSYS","proteome":"UP000805418","gene":"RXFP1","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0004930","name":"G protein-coupled receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007186","name":"G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0007165","name":"signal transduction","category":{"code":"P","name":"biological_process"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"2de1df406d3e5d3f9dd8ab9ac7e415e55535df71","counters":{"domain_architectures":16,"entries":23,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"smart":3,"ssf":2,"profile":2,"pfam":3,"cdd":1,"panther":1,"prints":2,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":16}}}