{"metadata":{"accession":"A0A8I3N426","id":"A0A8I3N426_CANLF","source_organism":{"taxId":"9615","scientificName":"Canis lupus familiaris","fullName":"Canis lupus familiaris (Dog)"},"name":"Ras-related protein Rab-4","description":["The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion"],"length":208,"sequence":"DFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRSAQAVAPQPCGC","proteome":"UP000805418","gene":"RAB4B","go_terms":[{"identifier":"GO:0003924","name":"GTPase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005525","name":"GTP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0032482","name":"Rab protein signal transduction","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"31aa1b32c82271990f81b4779ae58d1cb9b14b00","counters":{"domain_architectures":242492,"entries":19,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"profile":3,"smart":4,"ssf":1,"cathgene3d":1,"cdd":1,"ncbifam":1,"pfam":1,"panther":1,"prints":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":242492}}}