{"metadata":{"accession":"A0A8D6PNR8","id":"A0A8D6PNR8_9EURY","source_organism":{"taxId":"2546128","scientificName":"Methanocaldococcus lauensis","fullName":"Methanocaldococcus lauensis"},"name":"Cobyrinate a,c-diamide synthase","description":["Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source"],"length":441,"sequence":"MKRVVIAGTSSEVGKTVISTGIMKALSKKYNVQGYKVGPDYIDPTYHNIATGNKSRNLDSFFMNNEQIKYLFQKHSKNKDISIIEGVRGLYEGLSPIDDIGSTASIAKALDSPIILIVNAKSLTRSAIAIIKGFINFDNVKIRGVIFNFVRSEKHIKKLKEAMQYYLPDVEIVGFIPRNENFKVEGRHLGLVPTPENLEEINKKIETWGNLVEEYLDLEKIVEIADEDYEDIDDVFLWEINENYKKIGVAYDEVFNFYYWDIFDALKENKAKIEFFSPLNDCEVPDADILYIGGGYPELFKEELSNNKEMIESIREFDGYIYGECGGLMYLTKSIDNTPMVGLLNCSSIMDKKVQGLSYVKAEFLENCLIGRKGLTFKGHEFHYSKLVNIKEERFAYKILRGRGIINNLDGIFNGRVLAGYLHNHPVANPYFASSMVNFDG","proteome":"UP000679213","gene":"cbiA","go_terms":[{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0042242","name":"cobyrinic acid a,c-diamide synthase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"5409390d47827e87916aea66f2621f1f3e970ecf","counters":{"domain_architectures":26836,"entries":18,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cdd":2,"cathgene3d":1,"pfam":2,"profile":1,"ncbifam":3,"hamap":1,"panther":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":26836}}}