{"metadata":{"accession":"A0A8D2HKB6","id":"A0A8D2HKB6_UROPR","source_organism":{"taxId":"9999","scientificName":"Urocitellus parryii","fullName":"Urocitellus parryii (Arctic ground squirrel)"},"name":"Neuropeptide FF receptor 2","description":["Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system"],"length":420,"sequence":"MSEKWDSNSSENWYHIWSVNDTQHHLYSNNSITYVNYYLHHPQVAAIFIISYFLIFFLCMVGNSVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFRCVVHPFKPKLTIKTAFVIIVIIWVLAITIMSPSAVMLHVQEEKYYQVRINSQNKTSPVYWCREDWPHQEMRKIYTTVLFTTIYLAPLSLIVIMYGRIGISLFKSAVPHTGKQSQEQWHVVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYVDLSPNVLRIINIYIYPFAHWLAFCNSSVNPIIYGFFNENFRRGFQDAFQLQVCWKRGKPQEAYVLGARNNVLINTTAQLAREPEFQNPHGENLFYGKSAENPQKELAMEELGKAPKSNEM","proteome":"UP000694417","gene":"NPFFR2","go_terms":[{"identifier":"GO:0004930","name":"G protein-coupled receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007186","name":"G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0008188","name":"neuropeptide receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0031628","name":"opioid receptor binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0043408","name":"regulation of MAPK cascade","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0045761","name":"regulation of adenylate cyclase activity","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"587fa3dbe4504dc051049f3cca904dd9ab631b87","counters":{"domain_architectures":394800,"entries":14,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"smart":1,"pfam":1,"profile":1,"panther":1,"prints":3,"prosite":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":394800}}}