{"metadata":{"accession":"A0A8D2EE22","id":"A0A8D2EE22_THEGE","source_organism":{"taxId":"9565","scientificName":"Theropithecus gelada","fullName":"Theropithecus gelada (Gelada baboon)"},"name":"Peptide-methionine (R)-S-oxide reductase","description":["Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues","Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance"],"length":182,"sequence":"MARLLWLLRGLTLGAAPRRAVRGRAGGGEPCTGPVLGEAGSLATCELPLAKSEWQKKLTPEQFYVTREKGTEPPFSGIYLNNKEAGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTSGSDESHTGILRRLDTSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVALKFKPRKH","proteome":"UP000694411","gene":null,"go_terms":[{"identifier":"GO:0033743","name":"peptide-methionine (R)-S-oxide reductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016671","name":"oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006979","name":"response to oxidative stress","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0030091","name":"protein repair","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"deb4c5e8efd21b1ddf07e78fdbd67304e03e4fcf","counters":{"domain_architectures":33949,"entries":9,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"profile":1,"pfam":1,"panther":1,"ncbifam":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":33949}}}