{"metadata":{"accession":"A0A8C9VEI4","id":"A0A8C9VEI4_SCLFO","source_organism":{"taxId":"113540","scientificName":"Scleropages formosus","fullName":"Scleropages formosus (Asian bonytongue)"},"name":"Splicing factor YJU2","description":["Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex"],"length":344,"sequence":"MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQNELYLGLPIFRFYIKCTRCLAEITFKTDPENTDYAMEHGATRNFQAEKLIEEEEKKIQREREEEELNNPMKVLENRTRDSKMEMEVLENLQELKELNQRQAQVDFEGMLGRYKEEEEREKERQKEEDERETWEILEKALVKRLRDSDSDSDQEREQGKRKARSHIADKPTDFLTSTAAKTTDTQATNSLQGGVKHSHVETWERSVGGLNGGPLGQLVVRKKPGSSAPKSETATQLTAKSAQSKMDPKPTTSPANNTQPVAMQSVSSLSLLGAYSDTDDSE","proteome":"UP000694397","gene":"YJU2","go_terms":[{"identifier":"GO:0000398","name":"mRNA splicing, via spliceosome","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"2809d1d6aebac7a708cb152ebb2d2bf5436c0132","counters":{"domain_architectures":9588,"entries":5,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"hamap":1,"panther":1,"pfam":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":9588}}}