{"metadata":{"accession":"A0A8C9P210","id":"A0A8C9P210_SPEDA","source_organism":{"taxId":"99837","scientificName":"Spermophilus dauricus","fullName":"Spermophilus dauricus (Daurian ground squirrel)"},"name":"Alanine--glyoxylate aminotransferase 2, mitochondrial","description":["Multifunctional aminotransferase with a broad substrate specificity. Catalyzes the conversion of glyoxylate to glycine using alanine as the amino donor. Catalyzes metabolism of not L- but the D-isomer of D-beta-aminoisobutyric acid to generate 2-methyl-3-oxopropanoate and alanine. Catalyzes the transfer of the amino group from beta-alanine to pyruvate to yield L-alanine and 3-oxopropanoate. Can metabolize NG-monomethyl-L-arginine (NMMA), asymmetric NG,NG-dimethyl-L-arginine (ADMA) and symmetric NG,N'G-dimethyl-L-arginine (SDMA). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure"],"length":514,"sequence":"MTSAWRHLRRALCLETSSPRTSKLCPSLSPDASWISGTKHGLHSKPKMPPCDFLPEKYQSLAYNHILEIHKKHLSPVATAFFQKPLLLHQGHMEWLFDSEGNRYLDFFSGIVTVSVGHCHPKVNAAAQKQLGRLWHTSSVFFHPPMHTYAEQLSALLPEPLKVIFLVNSGSEANDLAMLMARAHSNNTDIISFRGAYHGCSPYTLGMTNVVAYKTGLSSGMGCRSTMCPDVFRGPWGGSHCRDSPAQTIRKCSCVPDCCQAKEQYIEQFKDTLNTSVAKSIAGFFAEPIQGVNGIVQYPKGFLKEAFKLVRERGGVCIADEVQTGFGRLGSHFWGFQTHDVMPDIVTMAKGIGNGFPMAAVVTTPEIARSLAKRLLHFNTFGGNPLACAIGSAVLEVIEEEKLQENCQEVGTYMLLKLAKLRDEFDIIGDVRGKGLMIGIEMVQDKMSRQPLPPQEVSQIHEDCKNMGLIVGRGGIFSQTFRIAPPMCITKPEVDFAVEVFRSALIQHMERRAK","proteome":"UP000694422","gene":null,"go_terms":[{"identifier":"GO:0030170","name":"pyridoxal phosphate binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"77cca87d6dced57500d02f1f72b680f70c660080","counters":{"domain_architectures":185394,"entries":13,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cdd":1,"ssf":1,"cathgene3d":2,"pfam":1,"panther":1,"pirsf":1,"prosite":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":185394}}}