{"metadata":{"accession":"A0A8C9J891","id":"A0A8C9J891_PANTA","source_organism":{"taxId":"74533","scientificName":"Panthera tigris altaica","fullName":"Panthera tigris altaica (Siberian tiger)"},"name":"Endothelial lipase","description":["Exerts both phospholipase and triglyceride lipase activities. More active as a phospholipase than a triglyceride lipase. Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins"],"length":500,"sequence":"MRNSVPLLCLWSVHCCFAAGSPTPPGPEGRLQDELRTPRNVQIVAKPLVRFNLRTSGDSEHEGCYLSLGHNQPLEDCGFNMTAKTFFIIHGWTMSGMFENWLYKLVSALQMREKEANVVVVDWLPLAHQLYTDAVNNTRVVGHSVARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPLFEGVDIHRRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKTRSKRNSKMYLKTRAGMPFRVYHYQMKIHIFSYKNMGDIEPNFYVTLYGTNADSQILPLEIVEQIGLNATNTFLVYTEEDLGDLLKIKLTWEGAAQSWYNLWKELRSYLSQPRSSERQLNIRRIRVKSGETQRRLTFCVEDLDHTSISPGQELWFHKCRDGWRMKNETSPTVELS","proteome":"UP000675900","gene":"LIPG","go_terms":[{"identifier":"GO:0016298","name":"lipase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006629","name":"lipid metabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0052689","name":"carboxylic ester hydrolase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004465","name":"lipoprotein lipase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"d4ea22200019edd9226c62d1d87f9a3f2f2ed418","counters":{"domain_architectures":5228,"entries":22,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"pfam":2,"cdd":2,"ssf":2,"profile":1,"smart":1,"pirsf":1,"panther":1,"prints":2,"interpro":8},"proteome":1,"taxonomy":1,"similar_proteins":5228}}}