{"metadata":{"accession":"A0A8C6WAN2","id":"A0A8C6WAN2_NANGA","source_organism":{"taxId":"1026970","scientificName":"Nannospalax galili","fullName":"Nannospalax galili (Northern Israeli blind subterranean mole rat)"},"name":"(Lyso)-N-acylphosphatidylethanolamine lipase","description":["Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine"],"length":355,"sequence":"MGWLCSTRRGLFTMADDLEQQPQGWLSSWLPTWRPTSMSQLKNVEARILQCLQNKFLARYVSLPNQNKIWTVTVSPEQKDRTPLVMVHGFGGGVGLWILNMDSLSTRRTLHTFDLLGFGRSSRPTFPRDPEGAEDEFVTSIETWRETMGIPTMILLGHSLGGFLATSYSIKYPERVKHLILVDPWGFPLRPTDPSEIRAPPTWVKAVASVLGRSNPLAVLRVAGPWGPGLVQRFRPDFKRKFADFFEDDTISEYIYHCNAQNPSGETAFKAMMESFGWARRPMLERIHLIRKDVPITMIYGANTWIDTSTGEKVKLQRPDSYVRDVEIEGASHHVYADQPHIFNAVVEEICNSVD","proteome":"UP000694381","gene":"Abhd4","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"4208e7859dea7ff67287230d6f84ba11d78c698d","counters":{"domain_architectures":386493,"entries":7,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"panther":1,"prints":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":386493}}}